Major new study identifies key protein driving Alzheimer’s disease

Photo caption: A breakthrough study reveals that the 1N4R tau isoform plays a critical role in Alzheimer’s disease. Photo credit: Alexander Raths via Shutterstock. Article by Joseph Shavit. The Brighter Side of News – March 2, 2025. Research article: Alzheimer’s & Dementia.

Alzheimer’s disease, a devastating neurodegenerative disorder, is closely linked to the accumulation of tau protein in the brain. When tau becomes hyperphosphorylated, it forms neurofibrillary tangles (NFTs), disrupting cellular processes and leading to cognitive decline. […]

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