New generation of cancer-preventing vaccines could wipe out tumors before they form

Photo by RF._.studio via Pexels. Article by Jocelyn Kaiser. Science – April 7, 2022.

Shots enter early clinical trials for healthy people at high risk for disease

When Dave Dubin learned at age 29 that he had colon cancer, it wasnt a big surprise. His grandfather and father had both survived the disease. “It was almost the Dubin way, and we just went on,” Dubin says. He had surgery and chemotherapy, but his cancer came back 10 years later. Genetic testing finally found an explanation for his family’s trials: a mutation in a DNA repair gene that lets genetic errors pile up in dividing cells. The disease, Lynch syndrome, comes with up to a 70% lifetime risk of cancer. […]

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