# Scientists Discover Plant Compound That Forces Aggressive Breast Cancer Cells Into Self-Destruction

- Link: https://www.widthness.com/scientists-discover-plant-compound-that-forces-aggressive-breast-cancer-cells-into-self-destruction/
- Published: 2026-03-03T09:00:00-06:00
- Author: Curated by John Wysocki

Image: DHL-11 competes with FANCI to bind IMPDH2, destabilizing it, reducing GMP synthesis, causing DNA damage and replication stress, and inducing TNBC cell apoptosis. Image credit: Yu Zhu, et al. via ScienceDirect. CC BY-NC-ND 4.0 (no modifications). Article by SciTechDaily.com. SciTechDaily – March 2, 2026. Research article: DHL-11, a novel prieurianin-type limonoid isolated from Munronia henryi, targeting IMPDH2 to inhibit triple-negative breast cancer. A newly discovered plant-derived molecule disrupts a critical cancer enzyme in an unconventional way. Scientists looking for new ways to tackle hard-to-treat breast cancers turned to an unexpected source: Munronia henryi, a plant known for producing limonoids, a family of complex natural compounds that plants often use for chemical defense. […] Click here to view original web page at www.scitechdaily.com Curated by John Wysocki See Full Bio