A new ADHD drug targets three brain chemicals instead of two. Here’s what that means

Diagram: Neurotransmitter – A chemical substance that is released at the junction of two neurons to transmit messages between neurons or from neurons to other cell types. Image credit: Explore Biology via Flickr. CC BY 4.0 (no modifications). Article by Jack Janetzki and Lisa Kalisch Ellett. The Conversation – August 12, 2026.

A new medicine for attention-deficit hyperactivity disorder (ADHD) has just entered the treatment toolbox: centanafadine, a once-a-day tablet sold under the brand name Simtriyo. It has been approved in the United States for adults and children aged six years and older but isn’t yet available in Australia. So how does it work? How is it different to other ADHD medications? And what are the potential side effects? […]

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