New Autism Treatment Strategy Restores Key Brain Receptor Function

Image credit: Polina via Pexels. Article by Institute for Basic Science. SciTechDaily – June 25, 2026. Research article: Nature Communications.

An antisense therapy that targets a glycine transporter restored NMDA receptor function in mouse models related to autism and in human brain organoids.

An overlooked protein that regulates levels of the amino acid glycine may hold the key to treating autism and other disorders linked to disrupted brain signaling. Researchers at the Institute for Basic Science (IBS) have shown that inhibiting the glycine transporter SLC6A20 can restore the activity of NMDA receptors, a major target of neuroscience research for decades. […]

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