Gene Therapy Restores Hearing in Those with Deafness

Image credit: Freepik via Freepik. Article by KI Press Office. Neuroscience News – July 3, 2025. Source: Karolinska Institute.

Summary: A new study shows that gene therapy can significantly improve hearing in both children and adults with congenital deafness caused by mutations in the OTOF gene. The therapy uses a synthetic virus to deliver a healthy copy of the gene directly to the inner ear, with hearing improvements observed in all ten participants within one month. Younger patients responded especially well, with one seven-year-old regaining near-normal hearing and conversational ability. The treatment was safe and well-tolerated, with no serious side effects reported during a 6–12 month follow-up. […]

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