Mini-Brains’ Reveal Autism’s Neuronal Imbalance Origins

Image credit: Neuroscience News. Article by Emily DeBoom. Neuroscience News – August 11, 2023. Source: Mayo Clinic. Original Research: Open access. “Modeling idiopathic autism in forebrain organoids reveals an imbalance of excitatory cortical neuron subtypes during early neurogenesis” by Alexandre Jourdon et al. Nature Neuroscience.

Summary: Scientists utilized organoids, or “mini-brains,” to explore the roots of autism spectrum disorder (ASD). Their study highlighted an imbalance of excitatory cortical neurons in the forebrains of ASD patients. This advanced technology mimics brain development alterations that occur in utero, potentially pinpointing when ASD begins. The findings build […]

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