New & old drug combo drops cholesterol by 49% in human trial

Illustration credit: brgfx via Freepik. Article by Paul McClure. New Atlas – May 18, 2025. Source: Cleveland Clinic.

Some people can’t get their bad cholesterol levels down, even if they take cholesterol-lowering meds. A new clinical trial using a combination of existing and not-yet-released cholesterol tablets lowered bad cholesterol by almost half in people at high risk of heart disease. We understand how high levels of low-density lipoprotein (LDL or “bad”) cholesterol can lead to plaque buildup on arteries, increasing the risk of a heart attack or stroke. […]

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